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KMID : 0352719960200040561
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Journal of Ginseng Research
1996 Volume.20 No. 4 p.561 ~ p.562
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Ginseng Research During Past 20 Years in Southeast Asia
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Yang, Ling Ling/Yang, Ling Ling
Yen, Kun Ying/Yen, Kun Ying
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Abstract
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Ginseng, the root of Panaz ginseng C.A. Meyer, is well-known oriental herbal medicine. The number of paper reporting the effects on its physiological, pharmacological, and behavioral effects has been increased every year, since ginsenosides isolated from ginseng are known to be biologically active components. This brief review summarizes some of new findings from recently published papers on ginsenosides or ginseng saponins. Therefore, this paper includes the various effects of gmsenosides on neuronal cell growths, on behavior of experimental animals, on enzyme activities, on the release and uptake of neurotransmitters, on neuronal cell excitability, on the motility of intestine, on antitumor activity, on cardiovascular system and metabolism. In spite of various effects of gmsenosides on various cells or organs, it is shill to date impossible for one to clearly explain the exact mechanism on the action of ginsenosides. However, in this article I will discuss several papers providing possible explanations on the physiological and pharmacological actions including signal transduction pathway of ginsenosides. The elucidation of the exact mechanism of ginsenosides´ on cellular or molecular level will not only give us a chance to explain why people have used ginseng as an elixir of life for several thousands of year but also give us a crucial chance to apply ginseng to modern medicine.
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